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3️⃣ Glutathione Rescue Normally, glutathione binds NAPQI and converts it into non-toxic byproducts (cysteine + mercapturic acid) that are excreted. 🟢 Example: Glutathione is your liver's “safety net” against toxins
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NAPQI - an overview
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Pharmacology 401 k Paracetamol NAPQI Glutathione COX3 Poisoning Antidote AcetylCysteine
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File:Acetaminophen metabolism.jpg
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acetaminophen glutathione GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. ❓How does
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Solved The stepwise mechanism below shows how glutathione
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Electrochemical evidences in oxidation of acetaminophen in the presence of glutathione and N-acetylcysteine
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