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flow trial semaglutide kidney outcomes 2024 nejm hazard ratio In the FLOW trial, researchers assessed whether the glucagon-like peptide 1 receptor agonist semaglutide was effective in preventing progression of kidney disease in patients with type 2 diabetes and chronic kidney disease

Marsoni M251S
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4.4 ★★★★★
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Verified Purchase
Peanut
Carnegie, US
★★★★★ 5
Adorable and so far tuff
My puppy 🐶 loves it. She's only had it a couple of days but so far she’s hasn’t ripped it apart.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 22, 2025
A
Verified Purchase
Aimee Rohn
Battle Creek, US
★★★★★ 5
Small
A little small but my dog loved them. Does not hold up to a shredder though. Perfect for typical toy lovers
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 18, 2026
B
Verified Purchase
Barbara Redcay
Waukegan, US
★★★★★ 5
Well made, sturdy toys
Color: 3 Pack Donkey Goat Dog
So cute! Sturdy too, great for tugs of war.
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Reviewed in the United States on May 8, 2026
J
Verified Purchase
Jordan
Dallas, US
★★★★★ 5
None of the stuffing pulled out
I have 3 dogs. 1 is very gentle w/ stuffed toys. 1 is new to us and very anxious and kept stealing things like water bottles to gnaw on. And 1 destroys every stuffed toy we have ever brought into the house. We bought these for the anxious one. She was recently adopted and very people shy and afraid of the world around her. She doesn't know how to play with people and she's terrified if you try to throw a ball or if you squeak a squeaker, but we also needed something durable enough for her chewing that would be safe for her and could also withstand the toy destroyer possibly getting hold of it. They've been playing with these for a few months now and the most damage is that some of the rope necks are a bit frayed and a lot of the fuzz on the outside is gone, but none of them have been torn open. And the squeakers are in there in a way that it's hard to make them squeak if not doing so intentionally. The 1 dog can have plush toys again, the 1 dog can gnaw and chew to reduce her anxiety and the 3rd can chew and attack it without me having to clean up stuffing all the time
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on August 6, 2022
C
Verified Purchase
Christane Huddleston
Boise, US
★★★★★ 4
Very durable
Color: 3 Pack Donkey Giraffe Dog
For some reason I thought they would be a little bigger but I have to say they are very durable. My Saint Bernard has not shredded them to pieces yet. Normally the toys last a day or two but he still has them after 3 weeks. 👍
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Reviewed in the United States on February 25, 2026

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