

glp-1 drugs in development Issue 42: GLP-1 RA Drug Development
Marsoni
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Friday, May 29
Safety warning over fake weight loss drugs GLP 1 Medications: Everything You Need to Know In four recent placebo controlled clinical trials, dysesthesia, an unpleasant sensation that's perceived on or under the skin, was reported as a side effect of the GLP 1 agonist semaglutide in 5 23% of recipients. Drug mechanism of action of GLP 1 analogues, DPP IV inhibitors, and Download Scientific Diagram Glucagon Like Peptide 1: An Introduction and Possible Implications for Neuropsychiatry The Journal of Neuropsychiatry and Clinical Neurosciences
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★★★★★ 3
Indestructible?
Color: Bacon, Color: Bacon
This is after 1 week of arrgressive chewing. Not sure if it's safe for my dog.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 27, 2026
★★★★★ 4
Beloved But Beware Microplastic Chip-Offs
Color: Bacon
My doodle adores this thing and gnaws on it constantly. He has not been able to harm it, which is great. That’s the best part. Things to be aware of:
1. This is mostly molded plastic; it is a bit heavy and very hard. My dog tosses it into the air and if it lands on him, it HURTS. A lot.
2. While it’s sturdy, sharp teeth eventually gnaw pieces and little shavings off the toy. These are microplastics and could be harmful if your dog swallows them.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 13, 2026
★★★★★ 5
Very sturdy chew toy
Color: Bacon
My Frenchy loves it! He’s not a large dog, but big for a French Bulldog. (32 lbs). He chews both ends, but prefers the snout. The eyes are cute, but began to peel off within the first week. I easily removed what was peeling. Half of the paint remained intact. When necessary, I will definitely replace it with the same toy.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 29, 2026
★★★★★ 5
Great chew toy, long lasting
Color: Bacon
This chew toy has been amazing. We have had it for 2 months with 2 dogs chewy on it and it is still going strong. We have a large Golden who chews on everything and and German Shepherd. Big dogs who chew aggressively. Very impressed! Would definitely buy again!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 25, 2026
★★★★★ 5
Buy it!
Color: Bacon, Color: Bacon
They love it! Very durable and a great squeaker that is seemingly indestructible! Definitely getting it in other colors, and impressed at the quality for the price. Don’t hesitate on this one- corgi and dachshund approved!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 29, 2026
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