glp-1 and ghrelin Gut hormones like ghrelin (↑ hunger) & GLP-1/PYY (↓ hunger) signal to the hypothalamus' arcuate nucleus. Orexigenic (AgRP/NPY) & anorexigenic (POMC/CART) neurons integrate these signals, regulating food intake via Y1/Y5 & Mc4

glp-1 and ghrelin Gut hormones like ghrelin (↑ hunger) & GLP-1/PYY (↓ hunger) signal to the hypothalamus' arcuate nucleus. Orexigenic (AgRP/NPY) & anorexigenic (POMC/CART) neurons integrate these signals, regulating food intake via Y1/Y5 & Mc4

Name: glp-1 and ghrelin Gut hormones like ghrelin (↑ hunger) & GLP-1/PYY (↓ hunger) signal to the hypothalamus' arcuate nucleus. Orexigenic (AgRP/NPY) & anorexigenic (POMC/CART) neurons integrate these signals, regulating food intake via Y1/Y5 & Mc4
Brand: www.sagebambo.com
SKU: 66018084286
Price: 27.70 USD
Availability: InStock
Rating: 4.5976 (2306 reviews)

Marsoni

M251S

$27.70

Get it in 3 business days with 1 day shipping. Friday, May 29

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I'm always looking for different treats for my three dogs (10, 20 and 30 pounds, I don't ever recall giving my dogs anything with a pumpkin flavor, so I decided to trythese i-paw pumpkin flavored treats (I got the rings). All three of my dogs took the treat immediately and went off into their separate corners to chew away (one of my dogs is pretty fussy, so I was surprised she took it without hesitation). I'm no expert in dog treat ingredients, but I didn't see anything on the ingredients list that looked objectionable. While advertised as a rawhyde replacement, these rings don't last anywhere near as long as a rawhide, so while my dogs didn't wolf them down as fast as a conventional treat, they weren't left occupied for the half hour that a rawhide of this size might have kept them entertained (except for one of my dogs, who took an hour to finish hers, but she only has 7 teeth left in her mouth, so that's not really a fair comparison). I wouldn't hesitate to order these treats again for my pups.

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Reviewed in the United States on May 29, 2025

Kelly

Massapequa, US

★★★★★ 4

Lab tested. Lab approved. WAY too expensive.

Size: 3.8 Ounce (Pack of 1), Style: Sweet Potato, Ring

My dog likes these. But they don't really last all that long. And the package only included 5-6 rings. So that's an expensive treat, when I can get a bag of 40 dental treats (5" sticks) for the same price. Would I buy these again? No

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Reviewed in the United States on May 29, 2025

Verified Purchase

Maria V. Ogoy

Port Orchard, US

★★★★★ 3

Picky

Size: 3.8 Ounce (Pack of 1), Style: Sweet Potato, Ring

I've got a picky dog. He likes what he likes. He liked them at first but then lost interest.

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Reviewed in the United States on June 1, 2026