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GLP‑1 and GIP are incretin hormones released from intestinal enteroendocrine cells after nutrient intake; they enhance glucose‑dependent insulin secretion and suppress glucagon, thereby reducing postprandial glycaemia. Both peptides are rapidly
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Figure 4 from Two incretin hormones GLP-1 and GIP: comparison of their actions in insulin secretion and β cell preservation
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GLP-1 & GIP Mechanism (Incretin effect) GLP-1 and GIP are incretin hormones released from the intestine after meals. They improve metabolic control by: • Enhancing glucose-dependent insulin secretion • Suppressing glucagon release •
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